产品货号:
Z20083
中文名称:
MCL1抗体
英文名称:
Anti-MCL1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-MCL1 Antibody |
| 指标别名 | EAT;Mcl 1;Mcl 1l;Mcl 1s Delta TM;MCL1;mcl1/EAT;MCL1L;MCL1S;TM |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | MCL1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Mcl-1 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human Mcl-1.The immunogen is located within amino acids 220 - 270 of Mcl-1. |
| 计算分子量 | 37kDa |
| 成分 | Mcl-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Mcl-1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival.While the mechanism by which Mcl-1 inhibits apoptosis is not known,it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak.Mcl-1 was originally identified in differentiating myeloid cells,but has since been shown to be expressed in multiple cell types.Mcl-1 is essential for embryogenesis and for the development and maintenance of B and T lymphocytes in animals.Mcl-1 exists as at least three distinct isoforms designated Mcl-1L,Mcl-1S and Mcl-1ES.In marked contrast to the larger isoform of Mcl-1,overexpression of Mcl-1S promotes cell death. |
| Uniprot ID | Q07820 |
| 基因名全称 | Myeloid cell leukemia sequence 1 (BCL2-related) |
| 蛋白名全称 | Myeloid cell leukemia sequence 1 (BCL2-related) |
| 推荐稀释比 | Mcl-1 antibody can be used for detection of isoforms Mcl-1L and Mcl-1ES by Western blot at 1 to 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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